Vaping linked to rare lung disease: study

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PARIS, Dec 5, 2019 (BSS/AFP) – Doctors treating a patient with a rare lung
disease usually caused by exposure to industrial metals say it may instead be
the first case linked to vaping.

Electronic cigarettes are sold as safer alternatives to traditional
tobacco products and as aids to stop smoking. But they have been implicated
in a growing number of recent deaths and health alerts, especially in the
United States.

Researchers at the University of California San Francisco said the patient
had hard-metal pneumoconiosis, typically found in people exposed to metals
such as cobalt or tungsten used in tool sharpening or diamond polishing.

It causes a persistent cough and breathing difficulties, and leaves tell-
tale scarring on lung tissue.

Kirk Jones, Clinical Professor of Pathology at UCSF, said “this patient
did not have any known exposure to hard metal, so we identified the use of an
e-cigarette as a possible cause.”

The case study, published in the European Respiratory Journal, said that
when researchers tested the patient’s e-cigarette, which was used with
cannabis, they found cobalt in the vapour it released, as well as other toxic
metals — nickel, aluminium, manganese, lead and chromium.

This was similar to other studies, suggesting that the metals were coming
from the heating coils found in vaping devices, rather than from any
particular type of re-fill — as has been previously thought.

“Exposure to cobalt dust is extremely rare outside of a few specific
industries,” Rupal Shah, assistant professor of medicine at UCSF, was quoted
as saying.

“This is the first known case of a metal-induced toxicity in the lung that
has followed from vaping and it has resulted in long-term, probably
permanent, scarring of the patient’s lungs,” he said.

– E-cigarettes ‘harmful’ –

An accompanying European Respiratory Society editorial on stopping smoking
rejected the use of e-cigarettes as an aid, saying it was “based on well-
meaning but incorrect or undocumented claims or assumptions.”

Editorial co-author Jorgen Vestbo, Professor of Respiratory Medicine at
the University of Manchester, said “E-cigarettes are harmful, they cause
nicotine addiction and can never substitute for evidence-based smoking
cessation tools.”

Commentators on the findings voiced reservations about making the link
based on just one case.

Professor John Britton, head of the UK Centre for Tobacco & Alcohol
Studies and a consultant in respiratory medicine at the University of
Nottingham, said that while cobalt could cause the disease “it is hard to see
how they reached this conclusion given that no cobalt particles were detected
in the lung samples from the patient.”

“This case is thus yet another example of serious lung disease in someone
using an electronic cigarette to vape cannabis,” he said, adding that the
risk in cases of people vaping nicotine “as an alternative to smoking tobacco
is very low.”

Earlier this year, the World Health Organization warned that electronic
smoking devices were “undoubtedly harmful and should therefore be subject to
regulation.”

In June, San Francisco became the first major US city to effectively ban
their sale and manufacture.